009-1 (ゼロゼロナイン・ワン Zero Zero Nine-One) is a spy-fi anime series based off of a manga series by famous manga artist Shotaro Ishinomori. It was first broadcast on TBS TV in Japan in October 2006. The original manga was named 009ノ1 (“Zero Zero Ku-no-ichi”; a pun on kunoichi and a reference to the main character’s occupation as a spy) and was serialized in Weekly Manga Action from 1967 to 1970, then returned briefly in 1974. It concerns Miléne Hoffman (ミレーヌ・ホフマン Mirēnu Hofuman; “Mylene” in the ADV translation), a female cyborg with machine gun breasts who works as a secret agent.
Brought to my attention by an advert on Facebook. (“She’s the super sexy spy … that will do anything for the mission”, apparently.)